{"id":209487,"date":"2020-04-17T13:33:14","date_gmt":"2020-04-17T08:03:14","guid":{"rendered":"https:\/\/www.colombotelegraph.com\/?p=209487"},"modified":"2020-04-20T01:42:54","modified_gmt":"2020-04-19T20:12:54","slug":"the-evolution-of-the-covid-19-in-sri-lanka-prospects-for-relaxing-many-constraints","status":"publish","type":"post","link":"https:\/\/www.colombotelegraph.com\/index.php\/the-evolution-of-the-covid-19-in-sri-lanka-prospects-for-relaxing-many-constraints\/","title":{"rendered":"The Evolution Of The Covid-19 In Sri Lanka & Prospects For Relaxing Many Constraints"},"content":{"rendered":"

By Chandre Dharmawardana<\/a> –<\/span><\/strong><\/p>\n

\"\"<\/a>

Dr. Chandre Dharmawardana<\/p><\/div>\n

[This is a shortened version of a more technical paper, 15-04-2020]<\/b><\/p>\n

An outbreak of a new type of\u00a0 <\/span>pneumonia like disease was first reported on 31st December 2019 from Wuhan City in the Hubei Province of China. It was identifies as caused by\u00a0 <\/span>a ‘Novel Corona Virus’ on 7th January 2020, and renamed Covid-19 on 11th February 2020. The WHO\u00a0 <\/span>upgraded\u00a0 <\/span>the disease to a pandemic on the 11th of March 2020.<\/p>\n

From then on, many countries all over the world rushed to impose social distancing, lockdowns and curfews to prevent the spread of the disease. Sri Lanka’s initial official\u00a0 <\/span>response to Covid-19 began on January 27 when quarantine measures were imposed on incoming air passengers. The first local case, a guide working with Italian tourists,\u00a0<\/span>was detected on 10th March, and the importance of methodically identifying transmission chains became clear. This can be more important than blindly testing populations looking for Covid-19 positive cases (see my article in the Island, 1st April).<\/p>\n

The government at first attempted to contain the people in their homes by declaring public holidays and extending them. However, from March 18th\u00a0 <\/span>the government began to impose curfews in Covid-19<\/span><\/a> hot spots, many being in areas to which returnees from abroad, travelers or religious teachers\u00a0<\/span>had arrived and irresponsibly\u00a0<\/span>ignored\u00a0<\/span>social distancing and quarantine\u00a0<\/span>requirements.\u00a0 <\/span>Other who hold irrational beliefs (e.g., that the disease is caused by non-humans working in consort with \u201cNaga beings\u201d) also ignored social distancing, wearing masks etc., and proposed inhaling herbal smoke and consuming broth made from \u201ctraditional rice\u201d for fighting\u00a0 <\/span>the disease!<\/p>\n

In Western countries too,\u00a0 <\/span>patterns of transmission through human chains proved important. Also,\u00a0<\/span>support workers who worked in multiple nursing homes were potential carriers\u00a0<\/span>for\u00a0<\/span>spreading the disease. Nearly half of the dead in Canada from Covid-19 are in nursing homes.\u00a0<\/span>Such transmission chains are not normally implemented in\u00a0 <\/span>simulation models that are used in epidemiology.\u00a0<\/span>Furthermore, some countries, when releasing daily data of “new cases\u201d do not separate out cases that appear in quarantined populations from cases that appear from within the general public. New cases detected in quarantined locations do not add to the growth of the epidemic and should be treated differently in epidemiological modeling. What are labeled as “Covid-19 cases\u201d in one country may not conform to the same labeling in another country.<\/p>\n

Many of the epidemiological simulation models in current use are well known in the physical sciences and in ecological studies (see Bolker,\u00a0<\/span>Ecological models and data<\/i>. Princeton University Press). They are applied to competing chemical reactions, polymerization processes, competing plant growth etc. Most\u00a0 <\/span>of these processes begin with a period of exponential growth which gets gradually dampened and\u00a0 <\/span>\u201cflattens out\u201d. That is, many growth processes that are very different at the “individual level”\u00a0<\/span>all display\u00a0<\/span>growth and saturation characteristics having a universal shape. The so called logistic model is one of the simplest models belonging to this class. Here we exploit this universality and use a more sophisticated version of such a model to study Sri Lanka’s Covid-19 data.\u00a0 \u00a0<\/span><\/p>\n

Data analysis and modeling<\/b><\/span><\/p>\n

The Epidemiology unit of Sri Lanka’s ministry of Health (EU-SLH) has provided authoritative documentation in\u00a0<\/span>monitoring the evolution of Covid-19 via its daily bulletins. The cumulative numbers, i.e., the \u201ctotal confirmed cases” reported by EU-SLH\u00a0 <\/span>data are displayed in Figure 1 (curve with squares).\u00a0<\/span><\/p>\n

The data from 10th of March to 15th April have been used in constructing our epidemiological model which can be constantly updated as new data comes in. It is clear that the trend in the data changes\u00a0 <\/span>from 25th to 30th March, and then resumes its upward trend though with a different rate. This bi-modal characteristic is seen in the daily-change figures as well, in spite of the\u00a0 <\/span>noisy nature of the data. This suggests two independent loci of infection, or the effect of government interventions to control the epidemic, occurring with a time lag.\u00a0<\/span><\/p>\n

Efforts have been made to\u00a0 <\/span>account for the fact that\u00a0<\/span>the \u201cconfirmed cases\u201d reported\u00a0 <\/span>daily by the EU-SLH includes new cases that appear among quarantined\u00a0 <\/span>people. If the quarantining is effective, such new cases should not \u201cpush the curve upwards\u201d and change the final flattening trend of the curves. For instance, on the 13th of April 15 new cases were reported, when the cumulative number of confirmed cases jumped from 218 to 233. However, all 15 new cases were from those already confined in quarantine centers, and hence cannot be included as infection loci for the public. A data curve corrected for such cases is given (with triangles) in the figure, and labeled \u201cconfirmed public cases\u201d. Using these sets of data, we give our model results, and predict the long-term behaviour (asymptotic behavior) and the number of cases to expect when the curve \u201cflattens\u201d, in each scenario.<\/p>\n

\"\"<\/a>

Figure 1. Models for the time evolution of the total number of Covid-19 cases, showing projected long-term behaviour for three types of data treatment.<\/p><\/div>\n

If we consider the data set labeled as \u201cconfirmed public cases\u201d, where Covid-19 cases arising among quarantined people are not considered relevant to the spread of the epidemic, then the long-time asymptote\u00a0 <\/span>is about 206, and definitely below 210. If all cases (the cumulative daily totals reported by the EU-SLHD) are included in fitting the model, then the projection is 298, and certainly below 310. On the other and, if only the initial data set (prior to the imposition of social distancing and curfews) were used, the asymptote\u00a0<\/span>is ~325, but alternative parameter choices giving even 600 are possible. This shows that social distancing and curfews were effective in constraining the evolution of the epidemic.<\/p>\n

\"\"<\/a>

Figure 2. A comparison of daily \u201cnew\u201d numbers of the model<\/p><\/div>\n

The model can now be used to predict the daily \u201cnew\u201d numbers from<\/p>\n

10th<\/sup> March onwards, and examine how well they agree with the observed data. Note that what was fitted was the cumulative daily totals, and not this differential quantity. Hence good agreement with<\/p>\n

the general trends in the daily \u201cnew\u201d numbers is a useful test of the quality of the model. Our model reproduces the rough bi-modal character of the observed data and the general trends (Fig. 2).<\/p>\n

Conclusion<\/b><\/span><\/p>\n

Assuming that that the hospital resources are able to handle even 500 cases, these studies suggest that Sri Lanka\u00a0 <\/span>should be able to resume nearly normal economic and civic activity by the end of the first week of May, assuming that the epidemic retains the characteristics shown in the current data. The confirmed new cases are arising mainly in\u00a0<\/span>hotspots in six districts, while the other districts seem\u00a0 <\/span>close to normal. Hence a graduated approach to opening the economy should be followed. Important civic activities like elections can be held while still imposing physical distancing. Sri Lanka’s economic rekindling is linked to domestic needs as well as those of\u00a0 <\/span>its foreign trading\u00a0 <\/span>partners.\u00a0<\/span><\/p>\n

The Covid-19 epidemic has created a situation where working online is becoming permanently\u00a0 <\/span>institutionalized, and this is environmentally very desirable\u00a0 <\/span>in reducing travel stress, particulate dust and combustion of fossil fuels. The re-opening\u00a0<\/span>should\u00a0<\/span>make all such desirable features a permanent characteristic of the economy.<\/p>\n","protected":false},"excerpt":{"rendered":"

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